The rightmost section of the image shows what hemagglutination looks like in the well of a microtiter plate (this is explained in greater detail further below). The picture below provides an example of hemagglutination. HA proteins on the surface of influenza viruses can bind to red blood cells and “glue” them together, forming a lattice structure (this is known as “hemagglutination”). Scientists use a test called the hemagglutination inhibition assay (HI test) to antigenically characterize influenza viruses. The Hemagglutination Inhibition Assay (HI Test) Genetic sequencing and Serology tests using human sera and genetic sequencing provide additional information about how similar circulating flu viruses are to vaccine viruses or other influenza viruses. This information also helps experts decide what viruses should be included in the upcoming season’s influenza vaccine. ![]() Antigenic characterization can give an indication of the flu vaccine’s ability to produce an immune response against the influenza viruses circulating in people. ![]() “Antigenic characterization” refers to the analysis of a virus’ antigenic properties to help assess how related it is to another virus.ĬDC antigenically characterizes about 2,000 influenza viruses during a typical flu season to monitor for changes in circulating viruses and to compare how similar these viruses are to those included in flu vaccines. The term “antigenic properties” is used to describe the immune response triggered by the antigens on a particular virus. ![]() When someone is exposed to an influenza virus (either through infection or vaccination) their immune system makes specific antibodies against the antigens on that particular influenza virus.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |